Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic MutationsAdam Z. Albitar 1, Wanlong Ma 1, Maher Albitar 1
1NeoGenomics Laboratories
Wild-type blocking PCR followed by direct sequencing offers a highly sensitive method of detection for low frequency somatic mutations in a variety of sample types.